Microporous Annealed Particle (MAP) Scaffold Pore Size Influences Mesenchymal Stem Cell Metabolism and Proliferation Without Changing CD73, CD90, and CD105 Expression over Two Weeks

Scientists demonstrated that MAP microgel diameter could be tuned to control scaffold pore size and, in turn, modulate MSC survivability, proliferation, metabolism, and migration, thereby enhancing bioactivity and guiding future applications of MAP for regenerative medicine.