Mesenchymal Stem Cell-Derived Mitochondria Enhance Extracellular Matrix-Derived Grafts for The Repair of Nerve Defect

[Small] The authors used three human induced pluripotent stem cells lines to generate complex skin organoids with stratified skin layers and pigmented hair follicles, with different efficacies.

[Journal Of Investigative Dermatology] Investigators achieved highly efficient COL7A1 editing in primary recessive dystrophic epidermolysis bullosa keratinocytes and fibroblasts from two patients homozygous for the c.6508C>T mutation.

[Experimental Dermatology] Researchers validated different engineered immortalized cell lines created from primary human keratinocytes as model systems to study epidermal function.