Anti-Tumor Effects of Chemically Modified miR-143 Lipoplexes in a Colorectal Cancer Pelvic Recurrence Mouse Model Are Mediated via Downregulation of Myristoylated Alanine-Rich C Kinase Substrate
Scientists used a mouse model bearing pelvic CRC adjacent to the rectum and investigated the anti-cancer effects of CM-miR-143 lipoplexes formulated from miRNA and a cationic liposome.
[Biogerontology] Investigators explored the possibility of inducing aging-associated features in cell types of the central nervous system using hiPSC technology.
[Journal Of Neuroscience] The authors reported using human tumor specimens and primary spheroids from male and female patients that GlialCAM, was differentially expressed in subpopulations of glioblastoma cells.
[Molecular Psychiatry] Investigators showed that the PTENG132D allele disrupted early neuroectoderm formation during the first several days of organoid generation, and results in deficient electrophysiology.