HES1 Promotes Aerobic Glycolysis and Cancer Progression of Colorectal Cancer via IGF2BP2-Mediated GLUT1 m6A Modification
Researchers found that HES1 expression was significantly higher in colorectal cancer (CRC) tissues than that in adjacent normal tissues. Moreover, high HES1 expression is associated with poor survival in CRC patients. HES1
[Biogerontology] Investigators explored the possibility of inducing aging-associated features in cell types of the central nervous system using hiPSC technology.
[Journal Of Neuroscience] The authors reported using human tumor specimens and primary spheroids from male and female patients that GlialCAM, was differentially expressed in subpopulations of glioblastoma cells.
[Molecular Psychiatry] Investigators showed that the PTENG132D allele disrupted early neuroectoderm formation during the first several days of organoid generation, and results in deficient electrophysiology.