Engineered Nanovesicles Expressing Bispecific Single Chain Variable Fragments to Protect against SARS-CoV-2 Infection

A novel bispecific CB6/dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing nonintegrin nanovesicles were constructed to target both the SARS-CoV-2 spike protein and the DC receptors for virus neutralization and immune activation.
[ACS Biomaterials Science & Engineering]
AbstractGraphical Abstract

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