HIF-1α Promotes Kidney Organoid Vascularization and Applications in Disease Modeling

For the vascularization study, kidney organoids were generated from hiPSCs. Researchers overexpressed hypoxia-inducible factor-1 α (HIF-1α) via plasmid transfection or treated dimethyloxallyl glycine in kidney progenitor cells to detect the endothelium.
[Stem Cell Research & Therapy]
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