Arachidonate 15-Lipoxygenase-Mediated Production of Resolvin D5n-3 DPA Abrogates Pancreatic Stellate Cell-Induced Cancer Cell Invasion

Using liquid chromatography–tandem mass spectrometry-based lipid mediator profiling pancreatic stellate cells as well as primary human cancer-associated fibroblasts expressed enzymes and receptors to produce and respond to specialized pro-resolving mediators.