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e.g. organoids

SERPINB3-MYC Axis Induces the Basal-Like/Squamous Subtype and Enhances Disease Progression in Pancreatic Cancer

Metabolome analyses unveiled a metabolic signature linked to both SERPINB3 and the basal-like/squamous subtype, characterized by heightened carnitine/acylcarnitine and amino acid metabolism, associated with poor prognosis in patients with PDAC and elevated cellular invasiveness.
[Cell Reports]
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