Developmental Potency of Human ES Cell-Derived Mesenchymal Stem Cells Revealed in Mouse Embryos Following Blastocyst Injection

Scientists injected GFP-tagged human ESC-derived MSCs (EMSCs) into mouse blastocysts. EMSCs survived well and penetrated both the inner cell mass and trophectoderm, correlating to the higher anti-apoptotic capability of EMSCs than hESCs.