NewslettersESC & iPSC NewsLoss of Cohesin Regulator PDS5A Reveals Repressive Role of Polycomb LoopsBy lbeveridge - December 12, 20230499Using a CRISPR screen in mouse embryonic stem cells, investigators found that the cohesin regulator PDS5A links transcriptional silencing by Polycomb and 3D genome organization.[Nature Communications]Full Article