Microbiota-Derived Butyrate Restricts Tuft Cell Differentiation via Histone Deacetylase 3 to Modulate Intestinal Type 2 Immunity

Investigators examined the impact of the microbiota on tuft cell biology in the intestine. Succinate induction of tuft cells and type 2 innate lymphoid cells was elevated with loss of gut microbiota.
AbstractGraphical Abstract