Microbiota-Derived Butyrate Restricts Tuft Cell Differentiation via Histone Deacetylase 3 to Modulate Intestinal Type 2 Immunity

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Investigators examined the impact of the microbiota on tuft cell biology in the intestine. Succinate induction of tuft cells and type 2 innate lymphoid cells was elevated with loss of gut microbiota.
[Immunity]
AbstractGraphical Abstract