Statins Affect Human iPSC-Derived Cardiomyocytes by Interfering with Mitochondrial Function and Intracellular Acidification

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Scientists investigated the effects of statins on human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-derived CMs). hiPSC-derived CMs were exposed to simvastatin, atorvastatin, rosuvastatin, and cerivastatin at increasing concentrations.
[Basic Research in Cardiology]
Abstract