Nicotinamide Phosphoribose Transferase Facilitates Macrophage-Mediated Pulmonary Fibrosis through the Sirt1-Smad7 Pathway in Mice

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A conditional knockout of nicotinamide phosphoribose transferase in lung macrophages curtailed the bleomycin-induced inflammatory responses and significantly mitigated pulmonary fibrosis.
[European Journal Of Pharmacology]
Abstract