Integrating Spatial and Single-Cell Transcriptomics to Characterize the Molecular and Cellular Architecture of the Ischemic Mouse Brain

Scientists used spatial transcriptomics to study the ischemic hemisphere in mice after stroke and sequenced the transcriptomes of 19,777 spots, allowing us to both visualize the transcriptional landscape within the tissue and identify gene expression profiles linked to specific histologic entities.
[Science Translational Medicine]
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