A Mammalian-Specific Alex3/Gαq Protein Complex Regulates Mitochondrial Trafficking, Dendritic Complexity, and Neuronal Survival

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By generating a CNS-specific armadillo repeat–containing X-linked protein 3 (Alex3) knockout mouse line, we demonstrated that Alex3 was required for the effects of Gαq on mitochondrial trafficking and dendritic growth in neurons.
[Science Signaling]
Abstract