Immune Cell-Derived Signals Governing Epithelial Phenotypes in Homeostasis and Inflammation

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The intestinal epithelium fulfills important physiological functions and forms a physical barrier to the intestinal lumen. Barrier function is regulated by several pathways, and its impairment contributes to the pathogenesis of inflammatory bowel disease (IBD), a chronic inflammatory condition affecting more than seven million people worldwide.
[Trends in Molecular Medicine]
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