IQGAP1 and NWASP Promote Human Cancer Cell Dissemination and Metastasis by Regulating β1-Integrin via FAK and MRTF/SRF

Scientists observed that β1-integrin was required for human prostate and breast cancer cell adhesion to endothelial cells (EC) under shear-stress conditions in vitro and to lung blood vessel ECs in vivo.
[Cell Reports]
Full ArticleGraphical Abstract