Methyl-CpG Binding Domain Protein 2 (Mbd2) Drives Breast Cancer Progression through the Modulation of Epithelial-to-Mesenchymal Transition

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To test whether Mbd2 plays a causal role in mammary tumor growth and metastasis, the authors performed genetic knockout (KO) of Mbd2 in transgenic mice and compared mammary tumor progression kinetics between the wild-type and KO groups.
[Experimental And Molecular Pathology]
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