HTRA1-Driven Detachment of Type I Collagen from Endoplasmic Reticulum Contributes to Myocardial Fibrosis in Dilated Cardiomyopathy

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RNA-sequencing analysis revealed an increased HtrA serine peptidase 1 (HTRA1) expression in patients with dilated cardiomyopathy which was strongly correlated with myocardial fibrosis.
[Journal of Translational Medicine]
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