Recycled Melanoma-Secreted Melanosomes Regulate Tumor-Associated Macrophage Diversification

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Scientists reported that melanoma-secreted melanosomes passaged through epidermal keratinocytes or dermal fibroblasts could be further engulfed by resident macrophages, which led to macrophage polarization into pro-tumor or pro-immune cell infiltration phenotypes.
[EMBO Journal]
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