Neutrophil-Derived PAD4 Induces Citrullination of CKMT1 Exacerbates Mucosal Inflammation in Inflammatory Bowel Disease

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Scientists employed single-cell RNA sequencing and substrate citrullination mapping to decipher the role of peptidyl arginine deiminase 4 (PAD4) in intestinal inflammation associated with inflammatory bowel disease.
[Cellular & Molecular Immunology]
Abstract