Spontaneous Differentiation of Human Induced Pluripotent Stem Cells to Odorant-Responsive Olfactory Sensory Neurons

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Researchers employed dual SMAD inhibition and fibroblast growth factor 8 along with N-2 and B-27 supplements in the culture medium to efficiently induce the differentiation of iPSCs into neuronal cells with olfactory function through olfactory placode.
[Biochemical And Biophysical Research Communications]
Abstract