Ferroptosis Exacerbates Hyperlipidemic Acute Pancreatitis by Enhancing Lipid Peroxidation and Modulating the Immune Microenvironment

The authors focus on the malignant development of hyperlipidemic pancreatitis with severe disease combined with the core features of ferroptosis to explore and describe the mechanism of this phenomenon and show that the activation of lipid peroxidation and the aberrant intracellular release of many inflammatory mediators during ferroptosis are the key processes that regulate the degree of disease development in patients with hyperlipidemic acute pancreatitis.
[Cell Death Discovery]
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