PI3K/HSCB Axis Facilitates FOG1 Nuclear Translocation to Promote Erythropoiesis and Megakaryopoiesis

Investigators identified heat shock cognate B as an indispensable protein for friend of GATA 1 (FOG1) nuclear translocation during erythropoiesis of K562 human erythroleukemia cells and cord-blood-derived human CD34+CD90+HSCs, as well as during megakaryopoiesis of the CD34+CD90+HSCs.