Single-Cell Patch-Clamp/Proteomics of Human Alzheimer’s Disease iPSC-Derived Excitatory Neurons versus Isogenic Wild-Type Controls Suggests Novel Causation and Therapeutic Targets

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A new single-cell patch-clamp/proteomics platform termed scPatch-Proteomics was developed on single neurons generated from hiPSCs bearing an Alzheimer’s disease genetic mutation.
[Advanced Science]
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