Extracellular Vesicles Activated Cancer-Associated Fibroblasts Promote Lung Cancer Metastasis through Mitophagy and mtDNA Transfer

The role and signaling pathways of tumor cell derived extracellular vesicles activating normal fibroblasts and the characteristic of induced cancer-associated fibroblasts were measured by the transmission electron microscopy, nanoparticle tracking analysis, immunofluorescence, and more.