iGATE Analysis Improves the Interpretability of Single-Cell Immune Landscape of Influenza Infection

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Scientists developed a new analytical approach iGATE based on probabilistic support vector machine classification. iGATE reveals that the 25 canonical immune cell types exhibit differential influenza infection susceptibility and replication permissiveness in vivo, but neither property varies with host genotype or aging.
[JCI Insight]
AbstractGraphical Abstract