Inhibition of HDAC Activity Directly Reprograms Murine Embryonic Stem Cells to Trophoblast Stem Cells

Researchers showed that treating mESCs with sodium butyrate increased the population of 2C-like cells and enabled direct reprogramming of ESCs into trophoblast stem cells without a transition through a 2C-like state.
[Developmental Cell]
Full ArticleGraphical Abstract