Hepatic Spheroid-on-a-Chip: Fabrication and Characterization of a Spheroid-Based in Vitro Model of the Human Liver for Drug Screening Applications

Researchers demonstrated an innovative microfluidic device for the formation, culture, and testing of hepatocyte spheroids, which comprises a large array of patterned microwells for hosting hepatic spheroid culture in a reproducible and organized format in a dynamic fluidic environment.