Lipotoxic Hepatocyte Derived LIMA1 Enriched Small Extracellular Vesicles Promote Hepatic Stellate Cells Activation via Inhibiting Mitophagy

High-fat diet (HFD) mice model was constructed to confirm the expression of LIMA1. The relationship between LIMA1-enriched LTH-small extracellular vesicles and LX2 activation was evaluated by measurement of fibrotic markers and related genes.