Glomerular Endothelial Cell Receptor ADGRF5 and the Integrity of the Glomerular Filtration Barrier

The impact of ADGRF5 deletion on glomerular morphology, kidney function, and glomerular endothelial gene/protein expression were analyzed using ADGRF5 knockout (Adgrf5−/−) mice and human primary glomerular endothelial cells.