Enhancing Chondrogenic Differentiation of Mesenchymal Stem Cells Through Synergistic Effects of Cellulose Nanocrystals and Plastic Compression in Collagen-Based Hydrogel for Cartilage Formation

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Investigators developed a hydrogel platform that incorporating cellulose nanocrystals within collagen and followed by plastic compression procedure to expel the excessive fluid out. This approach significantly improved the mechanical properties of the hydrogels and enhanced the chondrogenic differentiation of MSCs.
[International Journal of Biological Macromolecules]
AbstractGraphical Abstract