An Unbiased Ranking of Murine Dietary Models Based on Their Proximity to Human Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Researchers showed that Western diets aligned closely with human metabolic dysfunction-associated steatohepatitis (MASH); high cholesterol content, extended study duration and/or genetic manipulation of disease-promoting pathways are required to intensify liver damage and accelerate significant fibrosis development.