Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer

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Using the Hi-MYC prostate cancer mouse model, the authors demonstrated that an obesogenic high-fat diet rich in saturated fats accelerates the development of c-MYC–driven invasive prostate cancer through metabolic rewiring.
[Cancer Research]
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