Lysosomal Acid Lipase a Modulates Leukemia Stem Cell Response to Venetoclax/Tyrosine Kinase Inhibitor Combination Therapy in Blast Phase Chronic Myeloid Leukemia

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Investigators employed preclinical models of blast phase chronic myeloid leukemia to investigate the efficacy and underlying mechanism of leukemia stem cells-targeting with venetoclax/TKI combinations.
[Haematologica]
Abstract