Drug Evaluation of Parkinson’s Disease Patient-Derived Midbrain Organoids Using Mesoporous Au Nanodot-Patterned 3D Concave Electrode

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Midbrain organoids generated from Parkinson’s disease patient-derived iPSCs with gene mutations or normal midbrain organoids were positioned on the developed 3D concave electrode. The 3D concave electrode showed a 1.4 times higher electrochemical signal of dopamine compared to the bare gold electrode.
[ACS Sensors]
AbstractGraphical Abstract