β-Mangostin Targets and Suppresses Glioma via STING Activation and Tumor-Associated Microglia Polarization

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β-mangostin attenuated M2 polarization in BV2 cells and promoted M1-related interleukin (IL)-1β and IL-6 secretion, thereby inhibiting glioma invasion. β-mangostin improved the anti-glioma effects of αPD-1 and increased CD8+T cell and M1-type microglia infiltration.
[Biomedicine & Pharmacotherapy]
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