Tumor Microenvironment Reprogramming Improves Nanomedicine-Based Chemo-Immunotherapy in Sarcomas

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Scientists tested the mechanotherapeutic ketotifen combined with either pegylated liposomal doxorubicin or pegylated liposomal coencapsulated alendronate–doxorubicin plus anti–programmed cell death protein 1 antibody in mouse models of fibrosarcoma and osteosarcoma.
[Molecular Cancer Therapeutics]
Abstract