Early Rhombic Lip Protogenin^+ve Stem Cells in a Human-Specific Neurovascular Niche Initiate and Maintain Group 3 Medulloblastoma

Investigators identified a population of Protogenin-positive (PRTG+ve) MYChigh NESTINlow stem cells in the four-week-old human embryonic hindbrain that subsequently localized to the ventricular zone of the rhombic lip.