A Bispecific Nanosystem Activates Endogenous Natural Killer Cells in the Bone Marrow for Hematologic Malignancies Therapy

Researchers constructed a bone-marrow-targeting nanosystem, CSF@E-Hn, which is based on hematopoietic-stem-cell-derived nanovesicles adorned with gripper ligands and encapsulated with colony-stimulating factor for the treatment of hematologic malignancies.