Adaptor Protein CEMIP Reduces the Chemosensitivity of Small Cell Lung Cancer via Activation of an SRC-YAP Oncogenic Module

Researchers investigated whether and how cell migration-inducing hyaluronan binding protein (CEMIP) regulated the chemosensitivity of SCLC. Overexpression or knockdown of CEMIP in SCLC cells resulted in a notable increase or reduction in the IC50 value of cisplatin or etoposide, respectively.