MTGR1 Is Required to Maintain Small Intestinal Stem Cell Populations

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Using Mtgr1−/− mice, scientists assessed the effects of myeloid translocation gene related 1 (MTGR1) loss specifically in intestinal stem cell (ISC) biology. Loss of MTGR1 increased the total number of cells expressing Lgr5, the canonical marker of cycling ISCs, suggesting higher overall stem cell numbers.
[Cell Death & Differentiation]
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