Flexible Sono–Piezo Patch for Functional Sweat Gland Repair through Endogenous Microenvironmental Remodeling

Researchers developed a flexible sono–piezo patch that aimed to create an endogenous regenerative microenvironment to promote the repair of sweat glands in burn wounds. This patch utilized low-intensity pulsed ultrasound to activate electrical stimulation of the target tissue, resulting in enhanced pro-regenerative behaviors of niche tissues and cells, including peripheral nerves, fibroblasts, and vasculatures.