Qki5 Safeguards Spinal Motor Neuron Function by Defining the Motor Neuron-Specific Transcriptome via Pre-mRNA Processing

Motor neuron-specific ablation of the Quaking5 (Qki5) caused neurodegeneration in postnatal mice and loss of Qki5 function resulted in the aberrant activation of stress-responsive JNK/SAPK pathway both in vitro and in vivo.