Molecular Pathology, Developmental Changes and Synaptic Dysfunction in (Pre-) Symptomatic Human C9ORF72-ALS/FTD Cerebral Organoids

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Researchers generated iPSC-derived cerebral organoid models from C9-ALS/FTD patients, presymptomatic C9ORF72-HRE carriers, and controls.
[Acta Neuropathologica Communications]
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