Endolysosomal Dysfunction in Radial Glia Progenitor Cells Leads to Defective Cerebral Angiogenesis and Compromised Blood-Brain Barrier Integrity

Researchers used zebrafish embryos carrying a mutation in scavenger receptor B2, a highly conserved endolysosomal protein expressed predominantly in radial glia cells, to investigate the interplay among different neurovascular unit components.