Ectonucleotidase Activity Driven by Acid Ectophosphatase in Luminal a MCF-7 Breast Cancer Cells

Investigators showed that AMP dose-dependently inhibited p-nitrophenylphosphate (p-NPP) hydrolysis. The p-NPP and AMP hydrolysis showed similar biochemical behaviors, such as increased hydrolysis under acidic conditions and comparable inhibition by NiCl2, ammonium molybdate, and sodium orthovanadate.