CD73 Promotes Non–Small Cell Lung Cancer Metastasis by Regulating Axl Signaling Independent of GAS6

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Scientists demonstrated that the CD73/Axl axis could regulate Smad3-induced epithelial-to-mesenchymal transition to promote NSCLC metastasis. Mechanically, CD73 could be secreted via the Golgi apparatus transport pathway.
[Proceedings of The National Academy of Sciences of The United States of America]
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