Ascorbate Deficiency Increases Quiescence and Self-Renewal in Hematopoietic Stem Cells and Multipotent Progenitors

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Scientists showed that deletion of the Slc23a2 ascorbate transporter from hematopoietic cells depleted ascorbate to undetectable levels in HSCs and multipotent hematopoietic progenitors without altering plasma ascorbate levels.
[Blood]
Abstract