Phillyrin Inhibits Oxidative Stress and Neutrophil Extracellular Trap Formation through the KEAP1/NRF2 Pathway in Gouty Arthritis

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The authors investigated the therapeutic potential of phillyrin in gouty arthritis (GA) and explored its mechanisms of action. GA was induced in mice via intraarticular monosodium urate injection, and joint inflammation, inflammatory cell infiltration, and their level in serum/tissue were assessed.
[Immunologic Research]
AbstractGraphical Abstract